Cytopoint is an injection that starts controlling itch within 1 day and provides relief that lasts for 4 to 8 weeks*1

Cytopoint is a safe, effective, long-lasting treatment to help control itch due to allergic and atopic dermatitis. It is an injection that is given by your veterinarian that targets itch at its source.

Cytopoint works like your dog’s own immune system. It is specifically designed to target and neutralize one of the main proteins that send itch signals to your dog’s brain that triggers scratching, licking, and chewing. Cytopoint blocks signals that trigger allergic itch, so the constant scratching can stop so the skin has a chance to heal. In fact, in a study, Cytopoint helped damaged skin begin to heal within 7 days.1

4 to 8 weeks relief from itchy, irritated skin*
Within 1 day reduces signs of itching, such as scratching and licking1
Effective against allergic dermatitis and atopic dermatitis
Blocks a signal that triggers allergic itch2, 3
Maintains improvement in your dog’s skin condition
Tablet-free therapy. Can be given with other medications including vaccines

What makes Cytopoint different to other treatments, and how does it work?

Cytopoint is not like traditional pharmaceutical treatments for allergic dog itch. This biological medication is a protein, not a drug, that works like your dog’s own immune system to block the main protein that sends signals that trigger itch.2,3

The itch cycle in dogs with allergic itch

Cytopoint stops your dog from scratching by neutralizing itch messenger proteins in the blood, before they can trigger the itch signal. This helps your dog feel better as quickly as possible.

How will you know when it’s time for another Cytopoint injection?

You should schedule a progress exam with your veterinarian 4 weeks after the initial injection. However, every dog is different, so monitoring your dog’s scratching behaviour is important. If you see that the itch is acting up before the progress exam, call your veterinarian—your dog’s injection schedule may need to be adjusted.

The Cytopoint Allergic Itch Tracker can help you keep track of your dog’s itch. It’s simple to use and downloadable. Remember to take the tracker to your progress exam, so you can discuss the information with your veterinarian.

Cytopoint is safe for dogs of all ages

Cytopoint is safe to use in dogs of any age. It can also be used in dogs on many other commonly used medications, or dogs with other diseases.4 In fact, a clinical study showed dogs receiving Cytopoint had no more side effects than dogs receiving placebo (injections without medication).4 And since Cytopoint is not a drug-based treatment, it does not put pressure on the liver and kidneys.**

With Cytopoint, you gain the comfort of knowing every injection is delivered effectively and safely during an office visit. Your veterinarian administers a complete dose that helps relieve itch for up to 8 weeks,* making the treatment of this allergic skin condition easier for you to manage.

How long will my dog need Cytopoint treatment?

Some dogs have year-round disease and may need continuous treatment with Cytopoint, whereas other dogs may only need Cytopoint seasonally. You and your veterinarian should decide together what is best for your dog’s specific situation.

Frequently asked questions about Cytopoint

If you notice your dog is constantly scratching, licking, or chewing, it could be due to allergic or atopic dermatitis, a medical condition requiring professional treatment. Just like people, dogs can be allergic to common substances in the environment, such as grass and tree pollen, mold, and dust mites. Dogs may also be allergic to fleas, carpets, insecticides, and even ingredients in shampoos. These allergens can trigger itch and the cycle begins. It is important to make an appointment with your veterinarian to determine the cause of your dog’s allergic itch and discuss appropriate treatment. Learn more.
Cytopoint is specifically designed to target your dog’s itch at the source. It is an injection that controls allergic and atopic dermatitis for 4-8 weeks.*1
Cytopoint is not like traditional pharmaceutical treatments for allergic dermatitis. This biological medication is a protein, not a drug, that works like your dog’s own immune system to block the signals that trigger allergic itch.2,3
Cytopoint is available at your veterinarian’s office. It is an injection that is safely delivered right in the office for comfort, convenience and peace of mind.
Cytopoint works like your dog’s own immune system to relieve allergic dog itch. It blocks the protein that sends signals that trigger itch, so the constant scratching can stop. In studies, after one injection, Cytopoint started controlling itch within 1 day and provided relief. Cytopoint has also been shown to help damaged skin begin to heal within 7 days.1 See the cycle of allergic itch and how Cytopoint helps.
Some dogs have year-round disease and may need continuous treatment with Cytopoint, whereas other dogs may only need Cytopoint seasonally. You and your veterinarian should decide together what is best for your dog’s specific situation.
Just one Cytopoint injection starts controlling allergic itch within one day and provides relief that lasts for 4 to 8 weeks.*1 That means your dog may be able to go as long as 8 weeks between injections.1
Your veterinarian may schedule a progress exam four weeks after the first injection. But, it’s dependent on your dog’s individual needs. So, please consult your veterinarian.
Every dog is different, so monitoring your dog’s itch is important. If you notice your dog is frequently scratching, licking or chewing, you should call your veterinarian. Your veterinarian may want to adjust your dog’s Cytopoint injection schedule.
You can keep track of your dog’s allergic itch with the Cytopoint Itch Tracker. It’s simple to use and downloadable.
Yes! Cytopoint is safe to use in dogs of any age.
Cytopoint can also be used in dogs on many other medications or dogs with other diseases.4 As always, be sure to tell your veterinarian about all the medications your dog is taking.
A clinical study showed dogs receiving Cytopoint had no more side effects than dogs receiving placebo (injections without medication).4 Some of the most common side effects reported with both Cytopoint and placebo were dermatitis and bacterial skin infection.4 And since Cytopoint is not a drug-based treatment, it does not put pressure on the liver and kidneys.
As with any other treatment, it is good medical practice for the veterinarian to make an appropriate risk/benefit assessment for each individual patient when considering Cytopoint. Please contact your veterinarian if you would like to know more information or have questions about any potential adverse effects for Cytopoint.
There are several resources available for you to get more information on allergic dog itch.

*Repeat administration every 4 to 8 weeks as needed in the individual patient.1

References
  1. Michels, G. M., Ramsey, D. S., Walsh, K. F., Martinon, O. M., Mahabir, S. P., Hoevers, J. D., Walters, R. R. and Dunham, S. A. (2016), A blinded, randomized, placebo controlled, dose determination trial of lokivetmab (ZTS-00103289), a caninized, anti-canine IL-31 monoclonal antibody in client owned dogs with atopic dermatitis. Vet Dermatol. doi:10.1111/vde.12376
  2. Gonzales AJ, Humphrey WR, Messamore JE, et al. Interleukin-31: its role in canine pruritus and naturally occurring canine atopic dermatitis. Vet Dermatol. 2013;24(1):48-53. doi:10.1111/j.136S-3164.2012.01098.x.
  3. Olivry T, Bäumer W. Atopic itch in dogs: pharmacology and modeling. In: Cowan A, Yosipovitch G, eds. Pharmacology of Itch, Handbook of Experimental Pharmacology. 2015:357-369.
  4. Michels G.M., Walsh K.F., Kryda K.A., Mahabir s"p", Walters R.R., Hoevers j"d", and Martinon O.M: ' A minimally restricted, blinded, randomized, placebo-controlled trial of the safety of lokivetmab (ZTS-00103289), a caninized anti-canine IL-31 monoclona; antibody in client-owned dogs with atopic dermatitis (2016), Abstracts, Vet Dermatol, 27:6-121. doi: 10.1111/vde.12310
  5. HIII PB et al, Veterinary records 2006, 158 533-539